ANNA LUGANINI
Associate Professor
I graduated in Biology at the University of Turin in 2004. I then worked as the scientific consultant of the Swiss company Ribovax Biotechnologies aiming at the identification and characterization of human monoclonal antibodies neutralizing the human Cytomegalovirus (HCMV). After that, I obtained a Specialization in Microbiology and Virology and a PhD in Molecular Medicine at the University of Turin. Between 2008 and 2021 I was a Researcher at the Department of Life Sciences and Systems Biology of the University of Turin. I became Associate Professor in 2021.
Since the early stages of my career I have focused my research activities on three main areas of interest:
A. Analysis of transcriptional factors regulating the re-activation from the latent state in HCMV infection;
B. Study of phenotypic alterations of endothelial cells infected by HCMV;
C. Analysis of the role of the HCMV genes of the US12 family in the infection of several cell types relevant for the intra- and inter-host viral spread;
D. Identification, characterization, and validation of new antiviral compounds against DNA and RNA viruses.
TEACHING
GENERAL MICROBIOLOGY (course A and B) (SVB0024)
Bachelor Degree Course in Biology (L-13)
MICROBIOLOGY (MFN0738/A)
Bachelor Degree Course in Optics and Optometry
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MICROBIOLOGY AND HYGIENE (MFN0738)
Bachelor Degree Course in Optics and Optometry
GENERAL MICROBIOLOGY (MFN0404A)
Bachelor Degree Course in Biology (L-13)
CONTACTS
+39 0116704688
RESEARCH
THREE OF MY BEST RECENT PUBLICATIONS
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Luganini A., Di Nardo G., Munaron L., Gilardi G., Fiorio Pla A., Gribaudo G. (2018) Human cytomegalovirus US21 protein is a viroporin that modulates calcium homeostasis and protects cells against apoptosis. Proc Natl Acad Sci U S A., 115(52):E12370-E12377. doi: 10.1073/pnas.1813183115.
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Terlizzi ME., Occhipinti A., Luganini A., Maffei ME., Gribaudo G. (2016) Inhibition of herpes simplex type 1 and type 2 infections by Oximacro(®), a cranberry extract with a high content of A-type proanthocyanidins (PACs-A). Antiviral Res., 132:154-64. doi: 10.1016/j.antiviral.2016.06.006.
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Gariano GR., Dell'Oste V., Bronzini M., Gatti D., Luganini A., De Andrea M., Gribaudo G., Gariglio M., Landolfo S. (2012)
The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication. PLoS Pathog., 8(1):e1002498. doi: 10.1371/journal.ppat.1002498.