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GIULIA SIBILLE

Technician

I graduated in Biology and got my Master Degree in Medical Biotechnologies at the University of Turin. I obtained my PhD in Experimental Medicine and Therapy at the University of Turin. I joined LMV in 2019.


My research focuses on the identification and characterization of broad-spectrum antiviral compounds,

which will represent a valuable resource for future treatments of infections caused by several DNA and RNA viruses (e.g. Herpes Simplex Virus).

RESEARCH

antivirals (details)

THREE OF MY BEST RECENT PUBLICATIONS

  • Sibille G., Luganini A., Sainas S., Boschi D., Lolli M.L., Gribaudo G. The Novel hDHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis. Viruses 2022, 14: 2281. https://doi.org/10.3390/v14102281.

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  • Citarella A., Moi D., Pedrini M., Pèrez-Peña H., Pieraccini S., Dimasi A., Stagno C., Micale N., Schirmeister T., Sibille G., Gribaudo G., Silvani A., Passarella D., Giannini C., Passarella D. Synthesis of SARS-CoV-2 Mpro Inhibitors bearing a Cinnamic Ester Warhead with In Vitro Activity against Human Coronaviruses. Organic & Biomolecular Chemistry 2023, 21(18), pp. 3811–3824. https://doi.org/10.1039/d3ob00381g.

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  • Luganini A.*, Sibille G.*, Pavan M., Mello Grand M., Sainas S., Boschi D., Lolli M.L., Chiorino G., Gribaudo G. Mechanisms of Antiviral Activity of the New hDHODH Inhibitor MEDS433 Against Respiratory Syncytial Virus Replication. Antiviral Research 2023, 219: 105734. https://doi.org/10.1016/j.antiviral.2023.105734.

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